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Conceptual schema showing mitochondrial alteration in RTD induced pluripotent stem cells (iPSCs) and <t>iPSC</t> derived MNs and beneficial effects of RF + NAC treatment on mitochondrial morphology.
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Conceptual schema showing mitochondrial alteration in RTD induced pluripotent stem cells (iPSCs) and iPSC derived MNs and beneficial effects of RF + NAC treatment on mitochondrial morphology.

Journal: Antioxidants

Article Title: Mitochondrial Abnormalities in Induced Pluripotent Stem Cells-Derived Motor Neurons from Patients with Riboflavin Transporter Deficiency

doi: 10.3390/antiox9121252

Figure Lengend Snippet: Conceptual schema showing mitochondrial alteration in RTD induced pluripotent stem cells (iPSCs) and iPSC derived MNs and beneficial effects of RF + NAC treatment on mitochondrial morphology.

Article Snippet: Skin fibroblasts were reprogrammed, by non-integrating episomal technology (Epi Episomal iPSC Reprogramming Kit, A15960, ThermoFisher Scientific, Waltham, MA, USA), using nucleofection.

Techniques: Derivative Assay